SLU-PP-915 is an oral pan-ERR agonist research chemical. It copies exercise pathways to study mitochondrial biogenesis in preclinical laboratory models.
$199.00 $169.15
Out of stock
Want to be notified when this product is back in stock?
Modern Aminos offers high-purity SLU-PP-915 as a certified liquid reagent solution. This laboratory solution has been meticulously prepared to ensure chemical stability, structural identity, and precise analytical consistency across ongoing metabolic and nuclear receptor assay profiles.
SLU-PP-915 is a novel, small-molecule research compound classified as an exercise mimetic. In biochemical research, this term describes a laboratory agent that triggers the same genetic and cellular pathways that typically activate during sustained physical exertion.
When introduced to test tissue, SLU-PP-915 binds to and activates Estrogen-Related Receptors (ERRs), specifically the α, β, and γ isoforms. Despite the “estrogen” in the name, these are orphan nuclear receptors that do not interact with traditional reproductive hormones. Instead, they function as metabolic switches. When SLU-PP-915 activates these switches, it signals the cell to adapt by:
For researchers familiar with the first-generation pan-ERR agonist SLU-PP-332, SLU-PP-915 represents a major advancement in chemical engineering, primarily solving issues related to experimental delivery methods:
| Feature / Metric | SLU-PP-332 (First-Generation) | SLU-PP-915 (Next-Generation) |
|---|---|---|
| Target Receptor Affinity | Pan-ERR Agonist (α, β, γ) | Pan-ERR Agonist (α, β, γ) |
| Oral Bioavailability | Low-to-Moderate. Readily degraded by digestive enzymes, requires sublingual delivery or localized injection models to avoid degradation. | High. Chemically optimized to remain stable when processed orally in test models. |
| Transcriptional Synergy | Moderate baseline activation of mitochondrial genes. | Highly synergistic; significantly boosts the expression of exercise-responsive genes like Ddit4. |
| Primary Testing Model | Restrictive in vitro assays or invasive in vivo injection protocols. | Non-invasive, systemic in vivo oral dosing protocols. |
Verified material specifications for current laboratory batches:
| Chemical Parameter | Verified Specification Value |
|---|---|
| Full IUPAC Nomenclature | 2-(4-(2-(5-(cyclopropanesulfonamido)-1H-indol-3-yl)ethyl)phenoxy)-2-methylpropanoic acid |
| Molecular Formula | C23H26N2O5S |
| Molecular Mass (Molar Weight) | 442.53 g/mol |
| Receptor Binding Profile (EC50) | ERRα: ~414 nM | ERRβ: ~435 nM | ERRγ: ~378 nM |
| Purity Rating (HPLC) | > 98.7% Certified Pure Reagent Grade |
| Physical State | Clear, uniform liquid solution optimized for volumetric measurement |
Optimized for direct machine lookup and voice assistant indexing regarding research reagents.
The products offered by Modern Aminos are intended strictly for laboratory research purposes only and are sold exclusively to qualified professionals, institutions, and entities. These products are not for human consumption, veterinary use, or any other application involving living organisms, including but not limited to diagnostic, therapeutic, or recreational purposes.
By purchasing this product, you confirm that:
Modern Aminos does not claim that this product is approved by the U.S. Food and Drug Administration (FDA) for any purpose. The statements regarding this product have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
The buyer assumes full responsibility for ensuring the safe handling, storage, and use of this product. Modern Aminos is not liable for any damages, direct or indirect, resulting from improper handling, storage, or unauthorized use of this product. Furthermore, Modern Aminos reserves the right to refuse sales to any individual or entity suspected of misusing its products.
If you have questions about the safe and lawful use of this product, consult a qualified professional with expertise in laboratory research. By proceeding with this purchase, you agree to these terms and conditions.
