TAK-653 (osavampator, NBI-1065845; CAS 1358751-06-0) is a small-molecule research compound, C19H23N3O3S (MW 373.5 g/mol), classified in in-vitro studies as a positive allosteric modulator of AMPA-type glutamate receptors. Modern Aminos supplies TAK-653 for laboratory research use only, with third-party HPLC testing and a QR code on every vial to search for the corresponding COA.
For research use only. Not for human or veterinary use.
Buy TAK-653 online for research: third-party tested with COA by lot number.
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| Product name | TAK-653 |
|---|---|
| Synonyms / codes | Osavampator (INN/USAN); NBI-1065845; TAK 653; TAK653 |
| CAS number | 1358751-06-0 |
| PubChem CID | 56655833 |
| UNII | 9E3TOE5RIZ |
| Molecular formula | C19H23N3O3S |
| Molecular weight | 373.5 g/mol |
| IUPAC name | 9-[4-(cyclohexyloxy)phenyl]-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide |
| InChIKey | PXJBHEHFVQVDDS-UHFFFAOYSA-N |
| SMILES | CC1=CN2CCS(=O)(=O)N=C2C(=N1)C3=CC=C(C=C3)OC4CCCCC4 |
| Compound class | Small molecule; AMPA receptor positive allosteric modulator (in-vitro classification) |
| Certificate of analysis | Batch COA: scan the QR code on the vial or search the lot number at COA Batch Search |
TAK-653 is classified as an AMPA receptor positive allosteric modulator (also called an AMPA receptor potentiator). In in-vitro receptor and cell-based assays it is described as binding an allosteric site on AMPA-type glutamate receptors and increasing glutamate-evoked receptor responses, with minimal agonistic activity when glutamate is absent. Modern Aminos supplies TAK-653 solely as a reference compound for this kind of in-vitro laboratory work.
TAK-653, also called osavampator or NBI-1065845 (CAS 1358751-06-0), is a small-molecule research compound with the formula C19H23N3O3S and a molecular weight of 373.5 g/mol. It is classified as an AMPA receptor positive allosteric modulator and is sold by Modern Aminos for laboratory research use only.
TAK-653 is also known as osavampator (its INN) and NBI-1065845, and is often written as TAK 653 or TAK653. Its CAS number is 1358751-06-0, its PubChem CID is 56655833, and its InChIKey is PXJBHEHFVQVDDS-UHFFFAOYSA-N.
TAK-653 is an AMPA receptor positive allosteric modulator, also described as an AMPA receptor potentiator. In in-vitro assays it increases glutamate-evoked AMPA receptor responses while showing minimal agonistic activity on its own.
No. TAK-653 is a small molecule (a pyrazinothiadiazine dioxide derivative, C19H23N3O3S), not a peptide. It is sometimes grouped with research peptides because peptide suppliers also carry it.
Every TAK-653 batch is tested by an independent third-party laboratory using HPLC before release. The most recent published bulk-material COA (lot TA2601A, Vanguard Laboratory, reported March 31, 2026) shows 99.25% chromatographic purity.
Match the lot number on your vial label to the lot number on the COA. Then check the compound name, the testing laboratory, the report date, the method (HPLC-UV/VIS), and the result, which is chromatographic purity for bulk material or measured concentration for finished vials. Scanning the vial’s QR code opens the matching COA.
You can buy TAK-653 for research directly from this page at Modern Aminos, a US supplier. It is sold only to qualified researchers and institutions for laboratory use, and wholesale pricing is available through the Modern Aminos wholesale program.
US orders placed before 4 PM CT, Monday through Friday, ship the same business day via FedEx or UPS. Store TAK-653 as supplied, tightly sealed and protected from light, heat, and moisture.
Yes. TAK-653 is sold strictly for in-vitro laboratory research. It is not for human or veterinary use, is not a drug, food, or cosmetic, and is not approved by the FDA for any use.
For research use only. Not for human or veterinary use. TAK-653 is not a drug, food, cosmetic, or dietary product and is not approved by the FDA for any use. It is sold exclusively to qualified researchers and institutions for in-vitro laboratory research. By purchasing, you confirm you will handle it only in a controlled laboratory setting in compliance with all applicable laws.
The products offered by Modern Aminos are intended strictly for laboratory research purposes only and are sold exclusively to qualified professionals, institutions, and entities. These products are not for human consumption, veterinary use, or any other application involving living organisms, including but not limited to diagnostic, therapeutic, or recreational purposes.
By purchasing this product, you confirm that:
Modern Aminos does not claim that this product is approved by the U.S. Food and Drug Administration (FDA) for any purpose. The statements regarding this product have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
The buyer assumes full responsibility for ensuring the safe handling, storage, and use of this product. Modern Aminos is not liable for any damages, direct or indirect, resulting from improper handling, storage, or unauthorized use of this product. Furthermore, Modern Aminos reserves the right to refuse sales to any individual or entity suspected of misusing its products.
If you have questions about the safe and lawful use of this product, consult a qualified professional with expertise in laboratory research. By proceeding with this purchase, you agree to these terms and conditions.
